Silent 0 - victory vs. Time Eater:
I basically had a poison deck, featuring two Catalyst+ cards, a duplication potion, and a Runic Pyramid to retain my hand so I could Catalyst whenever I felt like it. On the last turn I had 1138 stacks of poison on the boss (he has 456 HP). that's dps, son
HGR later informed me that the boss clears all his debuffs when he hits half HP, which would have been disastrous. But I was a bit shy of the half-HP mark on the final turn so it turned out fine.
Thought: Runic Pyramid is really good. (Flashback to my previous failed run: After I defeated the Act 2 boss, HGR and newbie both left to get food, leaving me and numbers alone in the room. Together we looked at the boss rewards. One of them was Runic Pyramid. "Seems like a pain in the ass," I said. "Yeah," said numbers, "pain in the ass." So I took something else instead. Then HGR and newbie came back and heard I passed up Runic Pyramid and were like "whaaat??" Granted, Runic Pyramid wouldn't have saved that run; I just didn't have the damage no matter what cards I retained.)